Wolves' Helder Costa and Jonny Castro Otto earn debut international call-ups
Wolves winger Helder Costa has been called up to the senior Portugal squad for the first time.
And wing-back Jonny Castro Otto has also earned his debut Spain call-up as Wolves' international contingent expands.
Costa joined Wolves more than two years ago, initially on loan, and had previously featured for Portugal's youth sides but never the seniors.
The £13million man joins Ruben Neves and Rui Patricio in Portugal's squad to face Poland (in the Nations League) and Scotland (a friendly at Hampden), but Joao Moutinho is again left out by boss Fernando Santos who has also rested Cristiano Ronaldo.
Atletico Madrid loanee Jonny has been in fine form since moving to Wolves for the season in August.
He has started all seven Premier League games and scored his first Wolves goal to seal a 2-0 win over Southampton on Saturday.
The 24-year-old could face England in the Nations League during the international break, while Spain also have a friendly against Wales.
Ruben Vinagre has also been called up to the Portugal Under-21 squad for the first time, where he's joined by regular Diogo Jota. Vinagre won the Euro U19 Championship with Portugal this summer.
Matt Doherty and Raul Jimenez have also been called up to the Ireland and Mexico squads respectively.